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Recombinant Human TGF-beta 1 Protein

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R&D SYSTEMS

240-B-002

   Recombinant Human TGF-beta 1 Protein   

2ug

3502

现货

R&D SYSTEMS

240-B-010

Recombinant Human TGF-beta 1 Protein

10ug

10938



介绍:

作为胞外信号分子,TGF-beta1蛋白在多种细胞中进行表达,并作为胞外信号分子参与免疫功能,细胞增殖和细胞分化等生物学过程。1985年,作为公司推出的第一个科研试剂产品,也是全球第一家将该产品进行商业化生产的产品,R&D Systems成功上市了TGF-beta1蛋白。

Purity

>97%, by SDS-PAGE visualized with Silver Staining and quantitative densitometry by Coomassie® Blue Staining.

Endotoxin Level

<0.10 EU per 1 μg of the protein by the LAL method.

Activity

Measured by its ability to inhibit the IL-4-dependent proliferation of HT2 mouse T cells. Tsang, M.et al.

(1995) Cytokine 7:389. The ED50 for this effect is 0.04-0.2 ng/mL.

The specific activity of Recombinant Human TGF-beta 1 is approximately 2.5 x 104 U/μg, which is calibrated

against human TGF beta 1 Standard (NIBSC code: 89/514).

Source

Chinese Hamster Ovary cell line, CHO-derived human TGF-beta 1 protein Ala279-Ser390

Accession #

P01137

N-terminal Sequence Analysis

Ala279

Structure / Form

Disulfide-linked homodimer

Predicted Molecular Mass

12.8 kDa (monomer)

SDS-PAGE

12 kDa, reducing conditions


24 kDa, non-reducing conditions


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